India's Zydus Cadila begins human trials of COVID-19 vaccine candidate
Zydus Cadila said that it has begun giving its potential COVID-19 vaccine to healthy volunteers in the first and second phases of human clinical trials across multiple sites.
Indian drug firm Zydus Cadila on Wednesday said it has started human clinical trials of its COVID-19 vaccine candidate ZyCoV-D. In the phase of trials, the company will be enrolling over 1,000 subjects across multiple clinical study sites in India, it said in a regulatory filing. This comes as India for first time reported more than 29,000 new coronavirus patients in a single day.
The adaptive phase I/ II human clinical trials of ZyCoV-D have commenced with the first human dosing, it said, adding that “the adaptive phase I/II dose escalation, multi-centric study will assess the safety, tolerability and immunogenicity of the vaccine.”
Earlier this month, Zydus had received approval from domestic authorities to start human trials for its COVID-19 vaccine contender -- the second Indian pharmaceutical firm to get such nod amid a surge in novel coronavirus infections worldwide.
It got approval a few days after India's first indigenous COVID-19 vaccine candidate COVAXIN, developed by city-based Bharat Biotech in collaboration with Indian Council of Medical Research and National Institute of Virology, got the nod for human clinical trials from the Drug Controller General of India Shares of Cadila Healthcare, the listed entity of the group, were trading at Rs 356.50 a piece on BSE, up 0.81 per cent against their previous close, PTI reported.
INDIA RECORDS SINGLE-DAY SPIKE OF OVER 29,000 CASES
India registered a record single-day jump of 29,429 COVID-19 cases pushing its tally to 9,36,181 on Wednesday, while the death toll climbed to 24,309 with 582 new fatalities, according to the Union Health Ministry data.
#CoronaVirusUpdates: #COVID19 India Tracker— #IndiaFightsCorona (@COVIDNewsByMIB) July 15, 2020
(As on 15 July, 2020, 08:00 AM)
▶️ Confirmed cases: 936,181
▶️ Active cases: 319,840
▶️ Cured/Discharged/Migrated: 592,032
▶️ Deaths: 24,309#IndiaFightsCorona#StayHome #StaySafe @ICMRDELHI
Via @MoHFW_INDIA pic.twitter.com/vqsyZZqnc4
The number of recoveries stands at 5,92,031, while there are 3,19,840 active cases of coronavirus infection presently in the country, the updated data at 8 am showed.
"Thus, around 63.24 per cent of patients have recovered so far," an official said. The total number of confirmed cases include foreigners.
Of the 582 new deaths reported, 213 are from Maharashtra, 85 from Karnataka, 67 from Tamil Nadu, 43 from Andhra Pradesh, 35 from Delhi, 28 from Uttar Pradesh, 24 from West Bengal, 14 each from Bihar and Gujarat , 10 each from Madhya Pradesh and Telangana.
Punjab has reported nine fatalities followed by Jammu and Kashmir with eight, Assam, Haryana and Odisha four each, Jharkhand three, Chandigarh two while Arunachal Pradesh, Chhattisgarh, Goa, Kerala and Uttarakhand have reported one death each.